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tandfonline.com – The Limited Role of Formal Statistical Inference in Scientific Inference

tandfonline.com har udgivet en rapport under søgningen “Teacher Education Mathematics”: ABSTRACT ABSTRACT Such is the grip of formal methods of statistical inference—that is, frequentist methods for generalizing from sample to population in enumerative studies—in the drawing of scientific inferences that the two are routinely deemed equivalent in the social, management, and biomedical sciences. This, despite the fact that legitimate employment of said methods is difficult to implement on practical grounds alone. But supposing the adoption of these procedures were simple does not get us far; crucially, methods of formal statistical inference are ill-suited to the analysis of much scientific data. Even findings from the claimed gold standard for examination by the latter, randomized controlled trials, can be problematic. Scientific inference is a far broader concept than statistical inference. Its authority… Continue Reading

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tandfonline.com – Inference and Decision Making for 21st-Century Drug Development and Approval

tandfonline.com har udgivet en rapport under søgningen “Teacher Education Mathematics”: ABSTRACT Formulae display:?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. ABSTRACT The cost and time of pharmaceutical drug development continue to grow at rates that many say are unsustainable. These trends have enormous impact on what treatments get to patients, when they get them and how they are used. The statistical framework for supporting decisions in regulated clinical development of new medicines has followed a traditional path of frequentist methodology. Trials using hypothesis tests of “no treatment effect” are done routinely, and the p-value < 0.05 is often the… Continue Reading

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tandfonline.com – Why is Getting Rid of P-Values So Hard? Musings on Science and Statistics

tandfonline.com har udgivet en rapport under søgningen “Teacher Education Mathematics”: ABSTRACT ABSTRACT The current concerns about reproducibility have focused attention on proper use of statistics across the sciences. This gives statisticians an extraordinary opportunity to change what are widely regarded as statistical practices detrimental to the cause of good science. However, how that should be done is enormously complex, made more difficult by the balkanization of research methods and statistical traditions across scientific subdisciplines. Working within those sciences while also allying with science reform movements—operating simultaneously on the micro and macro levels—are the key to making lasting change in applied science. Link til kilde