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This paper describes a hypermedia resource, called MendelWeb that integrates elementary biology, discrete mathematics, and the history of science. MendelWeb is constructed from Gregor Menders 1865 paper, “Experiments in Plant Hybridization”. An English translation of Mendel’s paper, which is considered to mark the birth of classical and evolutionary genetics, is presented as an active document, with links to traditional reference material (e.g. glossaries, biographies, and the original German text) as well as images, tutorials, active commentaries, related Web sites, and animations. Users can choose to view any of several versions of the Mendel paper, each featuring different degrees of activity and annotation, and MendelWeb is designed to be accessible and useful to those running basic text browsers like Lynx, as well as full-featured browsers like Mosaic. MendelWeb, which is currently under construction at Brown University, is proposed not as an on-line textbook, but as a resource for teachers and students inside and outside traditional school environments. The links integrate elementary mathematics (i.e. probability and statistics), classical genetics, European history, and the history of early modern biology, in ways unavailable to traditional textbooks and even CD-ROM resources. MendelWeb will be valuable for teachers and students at the secondary and undergraduate levels, along with people of all ages pursuing independent studies. Finally, MendelWeb includes a series of project links, to encourage the construction of a larger web, tracing the history of genetics through the 19th, 20th, and into the 21st, centuries. MendelWeb can be accessed at http://netspace.org/. (Author/NB)